Lindsley F. Kimball Research Institute (LFKRI) is the research branch of New York Blood Center. Since its establishment in 1964, LFKRI's research efforts have paved the way for new blood-related products, techniques and therapies. The Institute's commitment to ground-breaking research has resulted in numerous landmark patents and licenses.
- Developed a practical screening method for hepatitis B as well as a safe, effective and affordable vaccine.
- Identified the hepatitis C virus, the so-called "naked virus" that causes many cases of cirrhosis, liver cancer and liver failure across the globe. It was only after researchers at LFKRI visualized and purified the virus that a means of treating it became possible.
- Created a solvent detergent procedure that is now used to inactivate viruses in blood plasma. This breakthrough has had an immeasurable impact on blood safety around the world by drastically reducing the risk of hepatitis and HIV transmission through plasma transfusions. The methodology was patented and licensed nonexclusively to more than 80 manufacturers.
- Detailed epidemiological studies on the prevalence of HIV infection in New York City and currently participating in HIV vaccine trials.
- Demonstrated the feasibility of using cord blood stem cells for transplantation. The clinical research performed using cord blood stem cells over the last 20 years has established the clinical utility of these cells as part of treatment regimens for a number of human diseases.
- Molecularly characterized a number of clinically relevant red cell blood group antigens.
- Developed mouse models of various red cell disorders including sickle cell disease to test the effectiveness of new therapeutic strategies.
LFKRI Continues at the Forefront of Health-Related Research
- Expanding the potential of transfusion medicine in the treatment of disease
- Developing new vaccines and prevention strategies against infectious diseases
- Detailing the genetics and functional significance of blood types
- Defining the utility of stem cells in transplantation and regenerative medicine
- Building on the unique resources of NYBC for promising research initiatives