Karina Yazdanbakhsh, PhD



Executive Director, Lindsley F. Kimball Research Institute
Member and Head of Laboratory

Research Area

Transfusion immunology
We are studying cellular immune responses to transfused blood products with the goal of developing strategies to prevent immune-mediated transfusion reactions.  Current research focus is on characterizing immunoregulatory networks that result in development of antibodies (alloimmunization) against transfused cells in transfusion-dependent patients with sickle cell anemia (SCA) and thalassemia. 

Platelet autoimmunity
We are characterizing the cellular and molecular pathways resulting in platelet autoimmunity in patients with immune thrombocytopenia (ITP) with the goal of developing new and improved treatments. Current research focus is on identifying immunological signatures of ITP drug response.  

Contact Information

Email: KYazdanbakhsh@nybc.org
Phone: +1 (212) 570-3383


Complement Biology

Lab Personnel

  • Emmanuelle Godefroy, PhD   Assistant Member
  • Yunfeng Liu, PhD  Research Fellow
  • Erika Choi  Research Assistant
  • Meredith Spadaccia, Research Technician

Funding Support

  • R01 HL121415 Yazdanbakhsh (PI) 8/1/2014– 4/30/2018 “T cell immunoregulation of alloimmunization in sickle cell Disease”

  • R01 HL122788 Yazdanbakhsh (PI) 09/01/2015-03/31/2019 “Immunopathology of ITP”

  • American Heart Association  Yazdanbakhsh (PI) 07/01/2014-06/30/2017 “Immunological Characterization of Transfusion dependent Patients with Sickle Cell Disease”

Education and Training

Doctoral Training
National Institute for Medical Research (MRC), Mill Hill, London, UK 

Postdoctoral Training
Columbia University, Rockefeller University